دانلود مقاله : Phage display antibodies for diagnostic applications 2013
دانلود مقاله :
Phage display antibodies for diagnostic applications 2013
نویسندگان :
Nur Hidayah Hairul Bahara , Gee Jun Tye , Yee Siew Choong , Eugene Boon Beng Ong , Asma Ismail , Theam Soon Lim
فرمت:pdf
چکیده :
With major developments in molecular biology, numerous display technologies have been successfully
introduced for recombinant antibody production. Even so, phage display still remains the gold standard
for recombinant antibody production. Its success is mainly attributed to the robust nature of phage
particles allowing for automation and adaptation to modifications. The generation of monospecific
binders provides a vital tool for diagnostics at a lower cost and higher efficiency. The flexibility to modify
recombinant antibodies allows great applicability to various platforms for use. This review presents
phage display technology, application and modifications of recombinant antibodies for diagnostics
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